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Alzheimer’s disease – uneventful dementia

posted on 11/29/2018 Facebook Facebook

Alzheimer’s disease is anirreversible, progressive neurological disorder that slowly destroysmemory and thinking skills, and eventually the ability to carry outbasic task. Alzheimer’s is most common cause of dementia amongolder adults (above 65 yrs).It is characterized as irreversible braindamage that disrupts typical cell function in the brain. The leadingtheory is that, in the case of Alzheimer’s abnormal deposits andfibers build up in the brain causing brain cell dysfunction andresulting cell death.

Forgetfulness or difficulty inremembering an event or process from your memory is prime symptom ofdisease – clinically termed as dementia. Routine tasks such aspreparing meals, remembering conversations and performing householdchores can be challenging. Additionally, it may become difficult torecognize people and name objects. Affected people increasinglyrequire help with dressing, eating and personal care.

According to the Alzheimer’sAssociation, about 5% of the patients with the disease haveearly-onset Alzheimer’s approximately before age of 50. For women,dementia is an especially important subject, as females have asignificantly higher risk (about twice as high as men) of developingthis cognitive condition. The numbers are staggering and do invokealarm since the disease is known to have no cure as yet.

Years of scientific research hasalso highlighted that Alzheimer’s may be genetic and hence run infamilies. Early onset Alzheimer disease is inherited in autosomaldominant pattern. Single copy of altered gene is sufficient to causedisorder. In most cases, an affected person inherits the altered genefrom one affected parent. Individual who inherit single copy of APOEe4 allele have an increased chance of developing Alzheimer’sdisease.

Genetic testing for the variousmutations linked to the disease can help determine yoursusceptibility. Knowing your risk can be seen as a chance to beinformed and take preventative steps to reduce it. Early detectioncan be a critical factor in management of disorder.


By:Ruchi Bhajeewala, Genetic Counselor, Positive Bioscience

Disclaimer:The opinions expressed in this blog are representative of the authorand may not express the views of Positive Bioscience. This blog isintended for education and information for the general public. Beforemaking any medical decisions a medical professional must beconsulted. All rights reserved. Image adapted from internet.

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