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  • EndoPredict is a genomic test that analyzes the activity of a group of genes that can affect how a cancer is likely to behave and respond to treatment.

  • It is used to help make treatment decisions based on the cancer's risk of coming back in a part of the body away from the breast (distant metastasis) within 10 years after diagnosis.

  • Knowing if a woman has a high or low risk of early-stage breast cancer coming back might help women and their doctors decide if chemotherapy or other treatments to reduce risk after surgery are needed.

  • The EndoPredict test measures the levels of 12 genes in breast cancer cells. These measurements are used to calculate an EP risk score that is then combined with the cancer tumor size and the nodal status of the cancer (how many lymph nodes tested positive for cancer). The result is the EPclin Score, which classifies the cancer as having a high risk or a low risk of the cancer metastasizing to an area of the body away from the breast.
  • Doctors interpret the EPclin Score as follows:

    • Cancers considered at low risk for distant metastasis may be able to be treated with hormonal therapy alone, allowing these women to avoid chemotherapy.
    • Cancers considered at high risk for distant metastasis should probably be treated with hormonal therapy and chemotherapy.

    You and your doctor will consider the EPclin Score in combination with other factors such as the grade of the cancer, the number of hormone receptors the cancer cells have (many versus few), and your age. Together, you can make a decision about whether or not you should have chemotherapy.

    • Endopredict helped me avoid Chemotherapy side effects and unwanted cost of treatment.

    • I was afraid of losing my hair to chemotherapy. My doctor advised me to take Endopredict to determine whether i need chemotherapy or not. Endopredict revealed that i fall in low risk category and i can be safely treated with hormonal treatment alone. I was relieved.

    • Having to undergo chemotherapy - that is a horrible experience that I would never wish on a woman.Your hair falls out, your blood count is unstable, and for months and months you feel miserable all the time. In addition, I do not know what long-term damage the chemotherapy may do to me. Of course, you want to take any therapy if it really helps! That‘s why, in my opinion, it‘s good that there is now a test that might spare us breast cancer patients from having to undergo unnecessary chemotherapy.


    EndoPredict provides information that allows physicians to:

    • Better understand a patients’ risk for specific health conditions

    • Prescribe more suitable medications at optimal dosages for patients, as needed.

    • Suggest early lifestyle and diet interventions to help control or prevent certain health conditions.


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